Reactive oxygen and nitrogen species are now acknowledged to play a key role in maintaining cellular and tissue physiology. At the same time, though, they can activate redox-dependent, signal transduction pathways involved in the development of a wide range of inflammatory and degenerative pathologies. Along these lines, a plethora of micronutrients with peculiar reducing properties have been recently shown to regulate cellular homeostasis effectively. First considered ‘health-promoting’ by virtue of their radical-scavenging activity and/or direct antioxidant effects on cellular biomolecules, such compounds are now believed to interfere with cellular signalling by intercepting reactive species at the level of critical redox-dependent pathways. Contributions are invited from investigators worldwide in the form of reviews or original research articles on the anti-oxidative effects and mechanisms through which micronutrients exert a positive impact on human health.
Prof. Mario Allegra and Dr. Ignazio Restivo
Università degli Studi di Palermo: Palermo, Sicilia, Italy
Moreira M., Pereira S., Guerra-Carvalho B., Carrageta D., Pinto S., Barros A., Silva B., Oliveira P., Alves M.
Cell Physiol Biochem 2022;56(S1):1-23
Ala M., Jafari R., Nematian H., Shadboorestan A., Dehpour A.
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Zalweska A., Ziȩba S., Kostecka-Sochoń P., Matczuk J., Żendzian-Piotrowska M., Maciejczyk M.
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Jiménez-Uribe A., Ocampo-Hernández A., Aranciba-Hernández Y., Pedraza-Chaverri J.
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